What Is The "blue pill" they give you in DR prior surgery?

Everyone talks about that “blue pill” you receive prior having a plastic surgery in Dominican Republic, however no one (clients) really knows anything about it, nor what it does.

We are not in “drug manufacturing” business, however we will do our best to try to explain, what it is, what it is used for and any side effects , if there are any. Well informed client is someone who is minimizing risks associated with the procedure they are about to have

“Blue Pill” as everyone calls it is actually a Dormicum Midazolam .

Midazolam is a short-acting hypnotic-sedative drug with anxiolytic, muscle relaxant, anticonvulsant, sedative, hypnotic, and amnesic properties.It belongs to a class of drugs called benzodiazepines. This drug is unique from others in this class due to its rapid onset of effects and short duration of action. Midazolam is available by oral, rectal, intranasal, intramuscular (IM), and intravenous (IV) routes and has been used in various biomedical applications, including dentistry, cardiac surgery, and endoscopic procedures as pre-anesthetic medication, and as an adjunct to local anesthesia.

This drug was initially approved by the US FDA in 1985, and has been approved for various indications since. In late 2018, the intramuscular preparation was approved by the FDA for the treatment of status epilepticus in adults.In May 2019, the nasal spray of midazolam was approved for the acute treatment of distinctive intermittent, stereotypic seizure episodes in patients 12 years of age and older. Midazolam is considered a schedule IV drug in the United States due to the low potential for abuse and low risk of dependence.

Important Information

Midazolam can slow or stop your breathing, especially if you have recently used a narcotic (opioid) medication. Midazolam is given in a hospital, dentist office, or other clinic setting where your vital signs can be watched closely.

You should not take midazolam if you have narrow-angle glaucoma, if you are allergic to cherries, or if you are allergic to midazolam or similar medicines (Valium, Xanax, Ativan, and others).

Do not drink alcohol for at least 24 hours after taking midazolam.

Before taking this medicine

You should not take midazolam if:

  • you have narrow-angle glaucoma;
  • you are allergic to cherries; or
  • you are allergic to midazolam or to other benzodiazepines, such as alprazolam (Xanax), chlordiazepoxide (Librium), clorazepate (Tranxene), diazepam (Valium), lorazepam (Ativan), or oxazepam (Serax).

To make sure midazolam is safe for you, tell your doctor if you have:

  • open-angle glaucoma;
  • asthma, emphysema, bronchitis, chronic obstructive pulmonary disorder (COPD), or other breathing problems;
  • kidney or liver disease;
  • congestive heart failure; or
  • if you also use a narcotic (opioid) medication.

Midazolam can cause birth defects in an unborn baby, and generally should not be used during pregnancy. Tell your doctor if you are pregnant.

Midazolam can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

How should I take midazolam?

Midazolam can slow or stop your breathing, especially if you have recently used a narcotic (opioid) medication. Midazolam should be used only in a hospital, dentist office, or other clinic setting where any serious side effects can be quickly treated.

Midazolam is usually given as a single dose just before your surgery or procedure.

After you take midazolam, you will be watched closely to make sure the medicine is working and does not cause harmful side effects.

Your breathing, blood pressure, oxygen levels, and other vital signs will be watched closely while you are in surgery.

Midazolam can make you very drowsy, dizzy, or light-headed. These effects may last longer in older adults. Use caution to avoid falling or accidental injury after you have received midazolam injection. You may need help getting out of bed for at least the first 8 hours.

What happens if I miss a dose?

Because you will receive midazolam in a clinical setting, you are not likely to miss a dose.

What happens if I overdose?

Seek emergency medical attention. An overdose of midazolam can be fatal.

Since this medication is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

What should I avoid while taking midazolam?

Do not drink alcohol for at least 24 hours after taking midazolam. This medication can increase the effects of alcohol, which could be dangerous.

Grapefruit and grapefruit juice may interact with midazolam and lead to potentially dangerous effects. Avoid the use of grapefruit products while taking midazolam.

Midazolam injection can cause extreme drowsiness that may last for 24 hours after you have received the medication. Older adults may feel sleepy for even longer.

Avoid driving or doing anything that requires you to be awake and alert until the effects of midazolam have worn off completely.

Midazolam side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Tell your caregivers right away if you have:

  • cough, wheezing, trouble breathing, weak or shallow breathing;
  • slow heart rate;
  • a light-headed feeling, like you might pass out;
  • agitation, hostility, tremors; or
  • confusion, hallucinations, unusual thoughts or behavior.

The sedative effects of midazolam may last longer in older adults. Accidental falls are common in elderly patients who take benzodiazepines. Use caution to avoid falling or accidental injury while you are taking midazolam.

Common side effects may include:

  • amnesia or forgetfulness after your procedure;
  • drowsiness, dizziness;
  • nausea, vomiting;
  • runny nose, sneezing; or
  • blurred vision.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

What other drugs will affect midazolam?

Shortly after you take midazolam, taking other drugs that make you sleepy or slow your breathing can cause dangerous side effects. Tell your doctor if you regularly use a sleeping pill, narcotic pain medicine, prescription cough medicine, a muscle relaxer, or medicine for anxiety, depression, or seizures.

Many drugs can interact with midazolam. Not all possible interactions are listed here. Tell your doctor about all your current medicines, especially:

  • anti fungal medicine;
  • an antibiotic;
  • an antidepressant;
  • heart or blood pressure medicine;
  • antiviral medicine to treat hepatitis C or HIV/AIDS;
  • seizure medication; or
  • tuberculosis medication.

This list is not complete and many other drugs can interact with midazolam. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.

Thank You For Reading

CroCaribe Recovery & Spa is a premier PostOp

Recovery House in Dominican Republic.

We provide a skilled clinical care in infection free settings following your surgery procedure.We have full time Medical Doctor on site, Accredited and Licensed English Speaking Nurses, HBOT (Oxygen Chamber/Therapy On Site),Power Generator on site so there is never a black out and our A/C is ALWAYS on. Our rained chef will follow all your dietary requirements and our recovery house is equipped with several EpiPens in event of an allergic reaction.

We implemented USA inspired infection prevention and control protocols, wound care protocols, emergency procedure protocols and skilled clinical care protocols. We are NOT a vacation destination, we are a skilled clinical care destination and we will ensure you receive clinical and customer service care you are accustomed and you deserve.

2 Responses

  1. This informations is especially helpful and certainly does allow for a more in-depth pre/post operative understanding.
    Thank you CCS for empowering the “Doll”” community with informative updates. Future CroCaribeSpa Guest

    1. Thank You…it is our pleasure. Knowledge is power and educated client has best chance to minimize or eliminate risks during the surgery and recovery process.


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